CLINICAL MANAGEMENT GUIDELINE

Irritable bowel syndrome with diarrhoea

ICD10: Irritable bowel syndrome with diarrhea [K58.0]

Treatment: Irritable bowel syndrome with diarrhea

IBS is a chronic disorder with primary manifestations of abdominal pain or discomfort and a change in bowel habits. It may be relieved with defecation. It may also be associated with abdominal distension, dyspepsia. IBS has a higher prevalence among the young population; especially, women.


How to use this plan: If the patient did not improve, switch to another class. If minimal improvement, add another supporting class.

Treatments

Level 1 / 1
pharmacological
eluxadoline
ROUTE
Oral
DOSE
100.000 mg
FREQUENCY
BID
pharmacological
alosetron
ROUTE
Oral
DOSE
0.500 mg
FREQUENCY
BID
pharmacological
rifaximin
ROUTE
Oral
DOSE
550.000 mg
FREQUENCY
Q8hr
pharmacological
Hyoscyamine
ROUTE
Oral
DOSE
125.000 μg
FREQUENCY
q6-12hr PNR
pharmacological
Dicyclomine
ROUTE
Oral
DOSE
10.000 mg
FREQUENCY
q8-12hr PRN
pharmacological
Amitriptyline
ROUTE
Oral
DOSE
10.000 mg
FREQUENCY
OD
prevention
Exercises
educational
Increased soluble fiber diet
educational
Dietary regime
prevention
Psychotherapy
educational
Probiotic therapy

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  • Duplicating mechanism of action of effect
  • Weight based dosing
  • Contraindication
  • Renal dosing
  • Interactions to drugs or diseases
  • Hepatic dosing

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